Author
UNSW SydneyORCID 0009-0004-8145-0691Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Golam Sarower Bhuyan, Feng Yan, Mary N.T. Nguyen…·John E. Pimanda
The paper identifies cell-state-specific mechanisms of 5-azacytidine response in myelodysplastic neoplasms, showing distinct differentiation and transcriptional changes in cycling progenitors and quiescent stem cells.
Henry R. Hampton, Anne Pan, Michael J. Carnell…·John E. Pimanda
The paper identifies NK-like CD8 T-cell expansion and CXCL12+ reticular cell remodeling as markers of azacitidine response in MDS through longitudinal bone marrow profiling.
Julie A.I. Thoms, Henry R. Hampton, Priscilla Li Shan Boon…·John E. Pimanda
This study uses single-cell multiomics to show that AZA response in MDS involves hematopoietic regeneration from mutated HSPCs and that AZA-refractive sub-populations contribute to disease progression.