Author

Sarah E. van Rossum-Fikkert

Erasmus MC

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

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Alex N. ZelenskyiD· 1 shared Arshdeep SidhuiD· 1 shared Claire WymaniD· 1 shared Hanny Odijk· 1 shared Maarten W. PauliD· 1 shared Roland KanaariD· 1 shared Yongxin LiangiD· 1 shared

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1 shared paperMolecular Biology

Alex N. ZelenskyORCID

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1 paper

Recent·Most cited

Molecular BiologyeLifePeer-reviewedJul 13, 2021

Role of BRCA2 DNA-binding and C-terminal domain on its mobility and conformation in DNA repair

Maarten W. Paul, Arshdeep Sidhu, Yongxin Liang…·Claire Wyman

This study examines how BRCA2's DNA-binding and C-terminal domains affect its mobility and conformation during DNA repair, showing that C-terminal deletions do not significantly impact mobility but impair architectural changes and homologous recombination function.

27 citations

mouseexperimental assay

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