Molecular BiologyeLifePeer-reviewed
Role of BRCA2 DNA-binding and C-terminal domain on its mobility and conformation in DNA repair
Maarten W. Paul, Arshdeep Sidhu, Yongxin Liang…·Claire Wyman
This study examines how BRCA2's DNA-binding and C-terminal domains affect its mobility and conformation during DNA repair, showing that C-terminal deletions do not significantly impact mobility but impair architectural changes and homologous recombination function.
27 citations