PRC1 Sustains the Memory of Neuronal Fate Independent of PRC2 Function
Ayana Sawai, Sarah Pfennig, Milica Bulajić, Alexander Miller, Alireza Khodadadi‐Jamayran, Esteban O. Mazzoni, Jeremy S. Dasen
The paper shows that PRC1 maintains neuronal subtype identity independently of PRC2, by preserving chromatin topology and transcriptional memory during differentiation.
eLife · Jan 7, 2022Peer-reviewedNeuroscience