Mutation-specific reporter for the optimization and enrichment of prime editing
Imre Firmin Schene, Indi P. Joore, Jan H. L. Baijens, Remi Stevelink, Gautam Kok, Sawsan Shehata, Eveline F. Ilcken, E. C. M. Nieuwenhuis, Dian Bolhuis, R. C. M. van Rees, Sacha Spelier, Hubert P. J. van der Doef, Jeffrey Matthijn Beekman, Roderick H.J. Houwen, Edward E. S. Nieuwenhuis, Sabine A. Fuchs
This paper introduces a fluorescent reporter system for evaluating and enhancing prime editing efficiency in genomic targets.
Nature Communications · Mar 1, 2022Peer-reviewedMolecular Biology