CRISPR-TRAPSeq identifies the QKI RNA binding protein as important for astrocytic maturation and control of thalamocortical synapses.
Kristina Sakers, Yating Liu, Lorida Llaci, Michael J. Vasek, Michael A. Rieger, Sean Brophy, Eric Tycksen, Renate M. Lewis, Susan E. Maloney, Joseph D. Dougherty
The paper uses CRISPR TRAPseq to show QKI is important for astrocytic maturation and synaptic control in vivo.
bioRxiv · Mar 13, 2020 · PreprintNeuroscience