Author

Sehar Afreen

University of Freiburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

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Andreas VillungeriD· 1 shared Claudia ManzliD· 1 shared Fabian SchuleriD· 1 shared Georg Alexander HäckeriD· 1 shared Miriam ErlacheriD· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperDevelopmental Biology

Andreas VillungerORCID

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1 paper

Recent·Most cited

Checkpoint kinase 1 is essential for fetal haematopoiesis and hematopoietic stem cell survival

Fabian Schuler, Sehar Afreen, Claudia Manzl, Georg Alexander Häcker, Miriam Erlacher, Andreas Villunger

This study shows that CHK1 is essential for hematopoietic stem cell survival and fetal hematopoiesis, and that its inhibition causes severe DNA damage and prevents HSC expansion.

EMBO Reports · Jun 17, 2019Peer-reviewedDevelopmental Biology