Georg Alexander Häcker

This study identifies SMAC as a regulator of cancer cell growth, inflammation, and mitochondrial integrity, showing its role in both apoptotic and non-apoptotic contexts.

This study shows that Chlamydia trachomatis uses membrane vesicles to deliver OmpA to mitochondria, inhibiting apoptosis and promoting bacterial survival in human cells.

This study shows that CHK1 is essential for hematopoietic stem cell survival and fetal hematopoiesis, and that its inhibition causes severe DNA damage and prevents HSC expansion.