Risk-free polio vaccine: Recombinant expression systems for production of stabilised virus-like particles
Lee Sherry, Mohammad W. Bahar, Claudine Porta, Helen Fox, Keith Grehan, Veronica Nasta, Helen M. E. Duyvesteyn, Luigi De Colibus, Johanna Marsian, Inga Kruse, Daniel Ponndorf, Seong-Ryong Kim, Sachin N. Shah, Sarah Carlyle, Jessica J. Swanson, , David J. Rowlands
This study produces stabilized poliovirus VLPs using recombinant systems, showing equivalent or better immunogenicity than current vaccines.
Nature Communications · Jan 18, 2025Peer-reviewedMicrobiology