Lee Sherry

Feline calicivirus encoding NanoLuc luciferase as a tool for assessing antibody neutralisation and antivirals

This paper develops a feline calicivirus reporter virus to assess antibody neutralisation and antivirals, identifying GS-441524 as a potential therapeutic.

Enhanced inter-chain hydrogen bonding in the murine norovirus VP1 capsid leads to increased particle stability and delayed viral uncoating

Inhibition of VP2-mediated entry: a potential antiviral strategy to treat or prevent calicivirus disease

This study demonstrates that inhibiting VP2-mediated entry reduces calicivirus infectivity, suggesting a potential antiviral strategy for treating norovirus disease.

Phosphorylation enables allosteric control of a viral condensate

This study shows that phosphorylation enables distinct nucleation mechanisms for NSP5 condensate formation in rotaviruses, depending on strain-specific LLPS propensity.

Upscaling production of immunogenic poliovirus virus-like particles in Pichia Pastoris by controlled fermentation

This study produces immunogenic poliovirus virus-like particles (VLPs) in Pichia pastoris through controlled fermentation, showing improved immunogenicity compared to current IPV vaccines.

A VLP vaccine platform comprising the core protein of hepatitis B virus with N-terminal antigen capture

The paper describes a modified nanoparticle vaccine platform, N-VelcroVax, which effectively binds SUMO-tagged antigens and shows potential as a vaccine scaffold.

Risk-free polio vaccine: Recombinant expression systems for production of stabilised virus-like particles

This study produces stabilized poliovirus VLPs using recombinant systems, showing equivalent or better immunogenicity than current vaccines.