Sepideh Heydarkhan‐Hagvall

This study compares the efficiency of cardiac-specific extracellular vesicles and lipid nanoparticles in delivering mRNA to the heart, finding that cardiac-specific vesicles are more effective with less liver accumulation.

The paper introduces a mouse model of advanced atherosclerosis that exhibits spontaneous plaque rupture leading to MI or stroke, and shows that MPO inhibition with AZM198 reduces mortality and plaque rupture incidence.