Syngap1 Synchronizes Relative Neuronal Maturation Across Cortical Areas to Organize Distributed Functional Networks
Randall M. Golovin, Bianca Garcia-Gonzalez, Sheldon D. Michaelson, Massimiliano Aceti, Seth Butz, Camilo Rojas, Courtney A. Miller, Thomas Vaissière, Gavin Rumbaugh
This study shows that Syngap1 haploinsufficiency in mice causes opposing cortical activity patterns, with reduced sensory responses and increased movement/arousal activity, revealing cell-type-dependent effects on network states.
bioRxiv · Mar 31, 2026 · PreprintNeuroscience