Bacteriophage self-counting in the presence of viral replication
Tianyou Yao, Seth Coleman, Thu Vu Phuc Nguyen, Ido Golding, Oleg A. Igoshin
The paper shows that bacteriophage lambda uses viral replication to reliably count infecting genomes, leading to lysogenic or lytic decisions based on multiplicity of infection.
Proceedings of the National Academy of Sciences · Dec 16, 2021Peer-reviewedSystems Biology