Ido Golding

Nuclear speckles comprise hierarchical nanoscale interaction networks that shape molecular dynamics

This study uses MINFLUX nanoscopy to show nuclear speckles are hierarchically organized into dynamic nanoscale interaction networks that regulate molecular dynamics.

Temporal dynamics of RNA phage infection reveal bacterial recovery despite ongoing viral replication

The paper studies RNA phage infection dynamics in E. coli, showing bacterial population rebound despite viral replication and cell death.

Cell Growth and Division Shape mRNA-Protein Correlations

The paper re-examines mRNA-protein correlations in E. coli, develops a theoretical framework accounting for cell growth and division, and validates it with simulations and data.

Single-phage profiling illuminates viral individuality during cell fate determination

The paper profiles individual phage transcription during E. coli infection to reveal how viral activity influences cell fate decisions between lysis and lysogeny.

Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle

The paper identifies a phage-encoded small RNA that regulates E. coli genes by hijacking host replication machinery during the phage lytic cycle.

Cytoplasmic localization of the mRNA encoding actin regulator, Serendipity-α, promotes adherens junction assembly and nuclear repositioning

The paper shows that mRNA localization of Serendipity-α promotes adherens junction assembly and nuclear repositioning during Drosophila embryo cellularization.

Transcription-replication interactions reveal principles of bacterial genome regulation

This study introduces a genome-wide classification of regulatory modes in bacteria by analyzing transcription-replication interactions, revealing new insights into gene expression dynamics and regulatory context.

Bacteriophage self-counting in the presence of viral replication

The paper shows that bacteriophage lambda uses viral replication to reliably count infecting genomes, leading to lysogenic or lytic decisions based on multiplicity of infection.