Author

Seungtae Lee

Biogipuzkoa Health Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Amaia López de ArbinaiD· 1 shared Antonella SpinazzolaiD· 1 shared Diego Pérez‐RodrígueziD· 1 shared Ian James HoltiD· 1 shared Leire Goicoechea Barrenechea· 1 shared Marina Villar-Fernandez· 1 shared Matthew E. GeggiD· 1 shared Mikel Muñoz‐OrejaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Amaia López de ArbinaORCID

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1 paper

Recent·Most cited

Elevated cholesterol in APOE4 astrocytes drives mitochondrial cristae collapse and ATP synthase dysfunction

Seungtae Lee, Mikel Muñoz‐Oreja, Marina Villar-Fernandez, Leire Goicoechea Barrenechea, Uxoa Fernández‐Pelayo, Diego Pérez‐Rodríguez, Matthew E. Gegg, Amaia López de Arbina, Antonella Spinazzola, Ian James Holt

This study shows that elevated cholesterol in APOE4 astrocytes causes mitochondrial cristae collapse and ATP synthase dysfunction, linking cholesterol imbalance to mitochondrial disease.

bioRxiv · Aug 4, 2026 · PreprintCell Biology