Author

Severin Graff

Forschungszentrum Jülich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 5

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Assay:electronic health records· 2 Research Focus:spatial domain detection· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Simon MusalliD· 5 shared Gerion NabbefeldiD· 4 shared Jenice LindeiD· 4 shared Can Bora YildiziD· 3 shared Geraldine Zimmer‐BenschiD· 3 shared Julia ReichardiD· 3 shared Anja UrbachiD· 2 shared Björn M. KampaiD· 2 shared

Activity by Year

2024-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersNeuroscience

Simon MusallORCID

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5 papers

Recent·Most cited

DNMT1 Coordinates PV Interneuron-Glia Coupling to Maintain Cortical Network Stability and Regulate Behavior

Jenice Linde, Can Bora Yildiz, Katharina Vöhringer, Gerion Nabbefeld, Severin Graff, Daniel Pensold, Julia Reichard, Marie Hermanns, Christoph Weber-Hamacher, Marc Spehr, Björn M. Kampa, Anja Urbach, Simon Musall, Geraldine Zimmer‐Bensch

This study shows DNMT1 maintains cortical network stability by regulating PV interneuron function and glial interactions, leading to behavioral changes when disrupted in mice.

bioRxiv · Nov 18, 2025 · PreprintNeuroscience

DNMT1-Mediated Regulation of Somatostatin-positive Interneuron Migration Impacts Cortical Architecture and Function

Julia Reichard, Philip Wolff, Song Xie, Ke Zuo, Camila L. Fullio, Jian Du, Severin Graff, Jenice Linde, Can Bora Yildiz, Georg Pitschelatow, Gerion Nabbefeld, Lilli Dorp, Johanna Vollmer, Linda Biemans, Shirley Kempf, , Geraldine Zimmer‐Bensch

This study shows that DNMT1 regulates the migration of somatostatin-expressing interneurons, affecting cortical layer structure and function in mice.

Nature Communications · Jul 24, 2025Peer-reviewedNeuroscience

UnitRefine: A Community Toolbox for Automated Spike Sorting Curation

Anoushka Jain, Robyn Greene, Chris Halcrow, Jake A. Swann, Alexander Kleinjohann, Federico Spurio, Severin Graff, Alejandro Pan-Vazquez, Björn Kampa, Jüergen Gall, Sonja Grün, Olivier Winter, Alessio Paolo Buccino, Matthias H. Hennig, Simon Musall

UnitRefine automates spike sorting curation using machine learning models trained on expert annotations, achieving human-level performance across species and datasets.

bioRxiv · Mar 30, 2025 · PreprintNeuroscience

Broadband visual stimuli improve neuronal representation and sensory perception

Elisabeta Balla, Gerion Nabbefeld, Christopher Wiesbrock, Jenice Linde, Severin Graff, Simon Musall, Björn M. Kampa

The paper shows broadband visual stimuli enhance neuronal responses and sensory perception in mice by reducing center-surround suppression in V1 and the superior colliculus.

Nature Communications · Mar 26, 2025Peer-reviewedNeuroscience

Dnmt1-deficiency in PV interneurons alters cortical circuit function and leads to depression-like behavior

Jenice Linde, Gerion Nabbefeld, Severin Graff, Can Bora Yildiz, Daniel Pensold, Julia Reichard, Marie Hermanns, Bjoern Kampa, Anja Urbach, Simon Musall, Geraldine Zimmer‐Bensch

This study shows that Dnmt1 deficiency in PV interneurons causes neural and behavioral changes associated with depression-like behavior.

bioRxiv · Sep 28, 2024 · PreprintNeuroscience