Daniel Pensold

This study shows DNMT1 maintains cortical network stability by regulating PV interneuron function and glial interactions, leading to behavioral changes when disrupted in mice.

This study shows that Dnmt1 deficiency in PV interneurons causes neural and behavioral changes associated with depression-like behavior.

The paper shows ephrinA5 reduces cell motility by decreasing Snhg15 expression, which lowers DNMT1 binding to the Ncam1 promoter, reducing methylation and increasing Ncam1 expression.

This study investigates how DNMT1 modulates proteostasis processes and affects neurodegeneration by impacting retrograde trafficking and autophagy.

This study shows that DNMT1 deletion in interneurons reduces age-related loss of cortical interneurons and improves somatomotor performance in mice.