Aging restricts colorectal tumor growth by epigenetically silencing developmental gene programs
Yang Liu, Venkataramana Thiriveedi, Saratchandra Singh Khumukcham, Babak Mirminachi, Reuben R. Cano, Oladimeji B. Aladelokun, Sahil Choudhri, Vyom Patel, Shahyan R. Khan, Shabna Mottemal, Nicholas O. Markham, Sajid A Khan, Caroline Helen Johnson, Sara A. Grimm, Jatin Roper, Paul A. Wade
This study shows aging restricts colorectal tumor growth by epigenetically silencing developmental gene programs, with implications for early-onset colorectal cancer.
bioRxiv · Jun 15, 2026 · PreprintCancer Biology