Author

Shaghayegh Fathi

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anthony J. CarlosiD· 1 shared Benoı̂t RouxiD· 1 shared Kavya Smitha PillaiiD· 1 shared Kyle GhabyiD· 1 shared Lydia BlachowicziD· 1 shared Mason FarmwaldiD· 1 shared Mukta SharmaiD· 1 shared Ngoc Kim Nguyen· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Anthony J. CarlosORCID

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1 paper

Recent·Most cited

Molecular Dynamics-Guided Design and Chemoproteomic Profiling of Covalent Kinase Activity Probes

Pratyasha Chakraborty, Anthony J. Carlos, Trayder Thomas, Kyle Ghaby, Shaghayegh Fathi, Mukta Sharma, Ngoc Kim Nguyen, Mason Farmwald, Lydia Blachowicz, Shaopeng Yu, Kavya Smitha Pillai, Benoı̂t Roux, Raymond E. Moellering

This paper designs and tests covalent kinase activity probes using computational methods and shows they target multiple kinases in live cells with distinct kinetics and conformations.

bioRxiv · Oct 17, 2025 · PreprintBiochemistry