TBK1 interacts with tau and enhances neurodegeneration in tauopathy
Measho H. Abreha, Shamsideen A. Ojelade, Eric B. Dammer, Zachary T. McEachin, Duc Minh Duong, Marla Gearing, Gary Jonathan Bassell, James J. Lah, Allan I. Levey, Joshua M Shulman, Nicholas T. Seyfried
This study identifies TBK1 as a tau-interacting kinase that enhances neurodegeneration in tauopathies through increased tau phosphorylation.
Journal of Biological Chemistry · Jan 1, 2021Peer-reviewedNeuroscience