Author

Measho H. Abreha

Emory University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

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Organism:human· 4 Research Focus:differential expression· 3 Assay:proteomics· 3 Approach:statistical model· 3 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Eric B. DammeriD· 4 shared Nicholas T. SeyfriediD· 4 shared Allan I. LeveyiD· 3 shared David Alan BennettiD· 2 shared Duc Minh DuongiD· 2 shared James J. LahiD· 2 shared Joshua M ShulmaniD· 2 shared Aditya NatuiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersNeuroscience

Eric B. DammerORCID

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4 papers

Recent·Most cited

Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease

Yona Levites, Eric B. Dammer, Yong Ran, Wangchen Tsering, Duc M. Duong, Measho H. Abreha, Joshna Dharmendrabhai Gadhavi, Kiara Lolo, Jorge A. Trejo‐Lopez, Jennifer Phillips, Andrea Iturbe, Aya Erquizi, Brenda D. Moore, Danny Ryu, Aditya Natu, , Todd Eliot Golde

The paper identifies a conserved Aβ amyloid 'responsome' in human and mouse AD brains, showing how amyloid scaffolds proteins involved in disease pathology.

Cell Reports Medicine · Aug 1, 2024Peer-reviewedNeuroscience

Integrated Proteomics Identifies Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease

Cheyenne D. Hurst, Derian A. Pugh, Measho H. Abreha, Duc Minh Duong, Eric B. Dammer, David Alan Bennett, Jeremy H. Herskowitz, Nicholas T. Seyfried

The paper identifies NRN1 as a mediator of cognitive resilience to Alzheimer's disease through integrative proteomic analysis and functional validation in neurons.

bioRxiv · Jun 15, 2022 · PreprintNeuroscience

TBK1 interacts with tau and enhances neurodegeneration in tauopathy

Measho H. Abreha, Shamsideen A. Ojelade, Eric B. Dammer, Zachary T. McEachin, Duc Minh Duong, Marla Gearing, Gary Jonathan Bassell, James J. Lah, Allan I. Levey, Joshua M Shulman, Nicholas T. Seyfried

This study identifies TBK1 as a tau-interacting kinase that enhances neurodegeneration in tauopathies through increased tau phosphorylation.

Journal of Biological Chemistry · Jan 1, 2021Peer-reviewedNeuroscience

Tau-mediated Disruption of the Spliceosome Triggers Cryptic RNA-splicing and Neurodegeneration in Alzheimer’s Disease

Yi‐Chen Hsieh, Caiwei Guo, Hari Krishna Yalamanchili, Measho H. Abreha, Rami Al‐Ouran, Yarong Li, Eric B. Dammer, James J. Lah, Allan I. Levey, David Alan Bennett, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M Shulman

This study shows that Tau disrupts the spliceosome, leading to cryptic RNA splicing and neurodegeneration in Alzheimer’s disease.

Cell Reports · Oct 1, 2019Peer-reviewedNeuroscience