Cell sorting based on single nucleotide variation enables characterization of mutation-dependent transcriptome and chromatin states.
Roberto Salatino, Marianna Franco, Arantxa Romero-Toledo, Ebba K. Blomqvist, Yi Wang, Shanel Tsuda, James M. Burke, Oszkar Szentirmai, Michalina Janiszewska
The paper develops STAR-FACS to sort cells by SNVs and shows distinct transcriptomes in glioblastoma cells with different TERT promoter mutations.
Nucleic Acids Research · Jul 31, 2025Peer-reviewedCancer Biology