Author

Shaojian Gao

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:multiome· 1

Frequent Co-Authors

Clara Kielkopf· 1 shared Dennis Liang Fei· 1 shared Harold Varmus· 1 shared Hayley Motowski· 1 shared Jovian Yu· 1 shared Rakesh Chatrikhi· 1 shared Robert K Bradley· 1 shared Sameer Prasad· 1 shared

Activity by Year

2016-2016 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Clara Kielkopf

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1 paper

Recent·Most cited

Cancer BiologybioRxivAug 24, 2016

Wild-type U2AF1 antagonizes the splicing program characteristic of U2AF1-mutant tumors and is required for cell survival

Dennis Liang Fei, Hayley Motowski, Rakesh Chatrikhi…·Harold Varmus

The paper shows that wild-type U2AF1 counteracts the splicing changes caused by the S34F mutation in lung cancer and is essential for cell survival, while the mutant protein is not required for growth.

DOI 10.1371/journal.pgen.1006384

humanmultiome

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