Cell BiologybioRxivPreprint
Ubiquitin-dependent recruitment of SLFN11 to chromatin is regulated by deubiquitinase and RNF168
Ukhyun Jo, Daiki Taniyama, Gianluca Pegoraro…·Yves G. Pommier
The paper identifies that DUB inhibitors and RNF168-mediated ubiquitylation drive SLFN11 chromatin recruitment, particularly at promoters, and that this process is suppressed by TAK243.
DOI 10.64898/2026.03.26.714477