Sharadyn Ille

Increased protein expression of methylenetetrahydrofolate reductase and cystathionine β-synthase in medial prefrontal cortical tissue of female vascular dementia patients

This study examines the impact of vascular dementia on one-carbon metabolism by measuring protein expression in brain tissue, finding gender-specific differences in enzyme levels.

Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice

This study shows that maternal dietary deficiency in choline or folic acid reduces MMP-2 levels in blood and brain tissue of male offspring mice after ischemic stroke.

Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, re-duced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring

This study examines how maternal dietary deficiencies in one-carbon metabolism affect ischemic stroke outcomes in middle-aged offspring, finding reduced neurodegeneration and neuroinflammation but no impact on motor function.