BioengineeringbioRxivPreprint
Dynamic Compression of Spheroid-Laden Alginate Granular Composites Induces Hypertrophic Chondrocyte Phenotype
David H. Ramos‐Rodriguez, Andrea C. Filler, Sheetal R Palle…·Jonathan Kent Leach
This study shows dynamic compressive loading of MSC spheroids in alginate scaffolds with dECM promotes hypertrophic chondrocyte phenotype and bone formation through YAP1 activation.
DOI 10.64898/2026.03.14.711819