Author

Erika E. Wheeler

University of California Davis Medical CenterORCID 0000-0002-0851-3535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Research Focus:trajectory inference· 2 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jonathan Kent LeachiD· 3 shared Kelly C. WeldoniD· 2 shared Thomas H. AmbrosiiD· 2 shared Yuting WangiD· 2 shared Amber N Maifeld· 1 shared Amin CressmaniD· 1 shared Andrea C. FilleriD· 1 shared Augustine M. SaiziD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioengineering

Jonathan Kent LeachORCID

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Author profile →

4 papers

Recent·Most cited

Spatiotemporal Control of Genetic and Epigenetic Editing through Covalent Tethering of CRISPR Nanoparticles to Zwitterionic Microgels

Joshua P. Graham, Erika E. Wheeler, Kent J. Leach, Tomas Gonzalez‐Fernandez

This paper introduces a method to covalently tether CRISPR nanoparticles to microgels for sustained and localized gene editing in human cells.

bioRxiv · Sep 22, 2026 · PreprintBioengineering

Bioorthogonal Tethering of FGF18 to Annealed Microgel Scaffolds Enhances Cartilage Repair

Erika E. Wheeler, Hye-Jeong Jang, Kelly C. Weldon, Kun Chen, Yuting Wang, Katherine H. Griffin, Thomas H. Ambrosi, Jonathan Kent Leach

This paper develops FGF18-tethered microgel scaffolds to enhance cartilage repair by optimizing surface charge and growth factor presentation.

bioRxiv · Aug 5, 2026 · PreprintBioengineering

Dynamic Compression of Spheroid-Laden Alginate Granular Composites Induces Hypertrophic Chondrocyte Phenotype

David H. Ramos‐Rodriguez, Andrea C. Filler, Sheetal R Palle, Shierly W. Fok, Erika E. Wheeler, Jonathan Kent Leach

This study shows dynamic compressive loading of MSC spheroids in alginate scaffolds with dECM promotes hypertrophic chondrocyte phenotype and bone formation through YAP1 activation.

bioRxiv · Mar 17, 2026 · PreprintBioengineering

Basigin Links Altered Skeletal Stem Cell Lineage Dynamics with Glucocorticoid-induced Bone Loss and Impaired Angiogenesis

Thomas H. Ambrosi, David Morales, Kun Chen, Ethan J. Hunt, Kelly C. Weldon, Amber N Maifeld, Fernando Sigler Chávez, Yuting Wang, Liming Zhao, Luke Wang, Matthew Philip Murphy, Amin Cressman, Erika E. Wheeler, Augustine M. Saiz, Jonathan Kent Leach, , Nancy E. Lane

This study identifies Basigin's role in GC-induced bone loss and impaired angiogenesis by linking altered skeletal stem cell dynamics to vascular dysfunction, showing that anti-Basigin therapy can reverse these effects.

Nature Communications · Aug 15, 2025Peer-reviewedCell Biology