NeuroscienceeNeuroPeer-reviewed
Sleep disruption precedes forebrain synaptic Tau burden and contributes to cognitive decline in a sex-dependent manner in the P301S Tau transgenic mouse model
Shenée C. Martin, Kathryn K. Joyce, Julia Sparks Lord…·Graham H. Diering
This study shows that sleep disruption accelerates cognitive decline in male P301S Tau mice but not females, without directly causing synaptic Tau pathology.
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