hpGRISZ: a high-performance fluorescent biosensor for in vivo imaging of synaptic zinc dynamics
Hao Zhang, Manoj Kumar, Raquel G. Correia, Shengjie Yang, Wenyuan Huang, Carina Soares‐Cunha, Patrick Andrew Cody, Yiyu Zhang, Xiaodong Tian, Shengyu Zhao, Mikhail A. Drobizhev, Ana João Rodrigues, Thanos Tzounopoulos, Hui‐wang Ai
The paper introduces hpGRISZ, a fluorescent biosensor for in vivo imaging of synaptic zinc dynamics, showing high responsiveness and suitability for detecting extracellular zinc release.
bioRxiv · Oct 6, 2025 · PreprintNeuroscience