GeneticsNeurobiology of DiseasePeer-reviewed
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors
Jia Jie Teoh, Narayan Subramanian, Maria Elena Pero…·Wayne N. Frankel
This study shows that Arfgef1 haploinsufficiency in mice reduces dendritic surface GABAAR and alters endosome composition, leading to increased seizure susceptibility.
11 citations