Damian J. Williams

The paper develops fluorescent reporters for human somatic sensory neuron subtypes to improve disease modeling of peripheral sensory neuropathy.

This study investigates the functional impact of SLC35A2 loss of function variants on glycomic signatures, neuronal fate, and network dynamics using human induced pluripotent stem cell-derived neurons.

This paper introduces a method to reversibly control neuronal activity using a light-activated saxitoxin inhibitor, demonstrating its effectiveness in altering behavior in zebrafish without genetic modification.

The paper investigates how a gain-of-function K+ channel variant causes seizures by reducing inhibitory neuron excitability and increasing network hyperconnectivity.

This study shows that Arfgef1 haploinsufficiency in mice reduces dendritic surface GABAAR and alters endosome composition, leading to increased seizure susceptibility.