Author

Shikuan Liang

Shandong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell signaling & trafficking· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Approach:biophysical modeling· 1

Frequent Co-Authors

Yulong SheniD· 5 shared Jinfeng NiiD· 4 shared Junfeng LiuiD· 3 shared Mart KrupovìčiD· 3 shared Pengju Wu· 3 shared Qunxin SheiD· 3 shared Yunfeng Yang· 3 shared Haodun Li· 2 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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5 shared papersMicrobiology

Yulong ShenORCID

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5 papers

Recent·Most cited

Transcription factor CCTF1 plays a decisive role in regulating the proteasome activity during archaeal cell division

Yunfeng Yang, Zixin Geng, Shikuan Liang, Haodun Li, Fan Zhou, Junfeng Liu, Mart Krupovìč, Yulong Shen

The paper identifies CCTF1 as a key regulator of proteasome activity during archaeal cell division by controlling PAN expression through promoter binding.

bioRxiv · Jun 5, 2026 · PreprintMicrobiology

Three transcription factors coordinate the archaeal cell cycle progression through a regulatory braking point mechanism

Yunfeng Yang, Shikuan Liang, Zixin Geng, Miguel V Gomez-Raya-Vilanova, Wenying Xia, Junfeng Liu, Qihong Huang, Jinfeng Ni, Qunxin She, Mart Krupovìč, Yulong Shen

This study identifies three transcription factors that regulate the archaeal cell cycle in Saccharolobus islandicus through a braking point mechanism, differing from eukaryotic regulation.

bioRxiv · Oct 16, 2025 · PreprintMicrobiology

Phosphorylation of the α subunit inhibits proteasome assembly and regulates cell division in an archaeon

Ya Chun Wu, Qi Gan, Kanghui Ning, Ran Zhang, Shikuan Liang, Yunfeng Yang, Pengju Wu, Xu Feng, Qunxin She, Jinfeng Ni, Yulong Shen, Qihong Huang

This study shows that phosphorylation of a proteasome subunit by ePK2 inhibits proteasome assembly and regulates cell division in Sulfolobales archaea.

bioRxiv · May 9, 2025 · PreprintMicrobiology

A new class of OLD family ATPases Cran1 functions in cell cycle progression in an archaeon

Yunfeng Yang, Shikuan Liang, Junfeng Liu, Xiaofei Fu, Pengju Wu, Haodun Li, Jinfeng Ni, Qunxin She, Mart Krupovìč, Yulong Shen

This study identifies a new class of OLD family ATPases in archaea, showing Cran1 is essential for cell cycle progression rather than antiviral defense.

bioRxiv · Mar 27, 2025 · PreprintMicrobiology

Identification of novel components of the Ced and Ups systems in Saccharolobus islandicus REY15A

Pengju Wu, Mengqi Zhang, Yanlu Kou, Shikuan Liang, Jinfeng Ni, Qihong Huang, Yulong Shen

This study identifies new components of the Ced and Ups systems in Saccharolobus islandicus REY15A and shows their roles in DNA import/export and cell aggregation.

mLife · Feb 1, 2025Peer-reviewedMicrobiology