Mengqi Zhang

This study shows that PCSK9 overexpression with high-fat diet in mice causes neurovascular dysfunction and cognitive deficits, including lipid-droplet accumulating microglia and vascular amyloid-beta deposition.

This study investigates the role of PATJ in cell stress responses and vascular remodeling after stroke using a mouse model and CRISPR-Cas9 knockout cells.

This study identifies new components of the Ced and Ups systems in Saccharolobus islandicus REY15A and shows their roles in DNA import/export and cell aggregation.

This study shows that targeting the VHL-HIF axis suppresses mortality and cellular damage caused by APOE4 and other stressors in C. elegans and mice.

The paper introduces IDEAS, a method for differential expression analysis in scRNA-seq data at the individual level, finding neurogranin-expressing neurons and ERBB signals in microglia are associated with autism.