A single dimer of the SARS-CoV-2 N protein can associate with multiple fragments of single-stranded and stem-loop RNAs
Naoya Kaneda, Leo Suzuki, Shun Endo, Syamil Muharror Ahsanul Husna, Shion Ishikawa, Hiroto Takahashi, Hiroyuki Oikawa, Yuji Itoh, Satoshi Takahashi
This study investigates how SARS-CoV-2 N protein interacts with different RNA structures, showing it can bind multiple RNA fragments per dimer and may help fold viral RNA into RNP granules.
bioRxiv · Jan 23, 2025 · PreprintBiophysics