Author

Shiwen Zhu

National University of Singapore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:zebrafish· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:protein structure· 1 Approach:simulation· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Cathleen TehiD· 2 shared Paul Thomas MatsudairaiD· 2 shared Sapthaswaran VeerapathiraniD· 2 shared Thorsten WohlandiD· 2 shared Bích Ngọc TrầniD· 1 shared Indira KartigayeniD· 1 shared Jun ZhongiD· 1 shared Timothy E. SaundersiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

Cathleen TehORCID

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2 papers

Recent·Most cited

Receptor binding and tissue architecture explain the morphogen local-to-global mobility transition

Shiwen Zhu, Yi Ting Loo, Sapthaswaran Veerapathiran, Tricia Y. J. Loo, Bích Ngọc Trần, Cathleen Teh, Jun Zhong, Paul Thomas Matsudaira, Timothy E. Saunders, Thorsten Wohland

The paper shows that tissue architecture and receptor binding can explain the transition from local to global morphogen diffusion, without needing additional regulatory mechanisms.

Biophysical Journal · Jul 24, 2024Peer-reviewedBiophysics

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Sapthaswaran Veerapathiran, Cathleen Teh, Shiwen Zhu, Indira Kartigayen, Vladimir P. Korzh, Paul Thomas Matsudaira, Thorsten Wohland

The paper investigates how Wnt3 spreads in the zebrafish brain through diffusion and molecular interactions, showing its binding to HSPG and Lrp5.

eLife · Nov 25, 2020Peer-reviewedDevelopmental Biology