Author

Paul Thomas Matsudaira

National University of SingaporeORCID 0000-0002-8399-3276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:zebrafish· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Approach:simulation· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Cathleen TehiD· 2 shared Sapthaswaran VeerapathiraniD· 2 shared Shiwen Zhu· 2 shared Thorsten WohlandiD· 2 shared Ana Sofia Dias MartinsiD· 1 shared Bích Ngọc TrầniD· 1 shared Francisco J. EnguitaiD· 1 shared Indira KartigayeniD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiophysics

Cathleen TehORCID

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3 papers

Recent·Most cited

Receptor binding and tissue architecture explain the morphogen local-to-global mobility transition

Shiwen Zhu, Yi Ting Loo, Sapthaswaran Veerapathiran, Tricia Y. J. Loo, Bích Ngọc Trần, Cathleen Teh, Jun Zhong, Paul Thomas Matsudaira, Timothy E. Saunders, Thorsten Wohland

The paper shows that tissue architecture and receptor binding can explain the transition from local to global morphogen diffusion, without needing additional regulatory mechanisms.

Biophysical Journal · Jul 24, 2024Peer-reviewedBiophysics

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Sapthaswaran Veerapathiran, Cathleen Teh, Shiwen Zhu, Indira Kartigayen, Vladimir P. Korzh, Paul Thomas Matsudaira, Thorsten Wohland

The paper investigates how Wnt3 spreads in the zebrafish brain through diffusion and molecular interactions, showing its binding to HSPG and Lrp5.

eLife · Nov 25, 2020Peer-reviewedDevelopmental Biology

Genome-wide Associations of Flavivirus Capsid Proteins

Priscilla Li Shan Boon, Ana Sofia Dias Martins, Francisco J. Enguita, Xin-Ni Lim, Nuno C. Santos, Paul Thomas Matsudaira, Ivo Cristiano Martins, W. Yue, Peter John Bond, Roland G. Huber

The paper maps the genome-wide association of capsid proteins with viral RNA in Dengue and Zika viruses, showing non-uniform binding patterns and sequence preferences.

bioRxiv · Apr 11, 2019 · PreprintGenomics