Vladimir P. Korzh

From patterning to secretion: Kv2.1 subunits as regulators of zebrafish hatching gland morphogenesis and function

This study shows that Kv2.1 subunits are essential for zebrafish hatching gland development and function, with their loss causing delayed hatching and secretion defects.

Kv2.1-Kv6.4 subunits deficiency impairs inhibitory signaling and visual circuit dynamics in zebrafish

This study shows that Kv2.1 subunit mutations in zebrafish impair inhibitory signaling and alter visual circuit dynamics, leading to behavioral and electrophysiological changes.

Kcnb1-Kcng4 axis regulates Scospondin secretion and Reissner fiber development

The paper shows Kv2.1 negatively regulates Scospondin secretion and Reissner fiber assembly in zebrafish through interactions with cholesterol and signaling pathways.

Mutant analysis of Kcng4b reveals how the different functional states of the voltage-gated potassium channel regulate ear development

The paper studies two mutations in the zebrafish Kcng4b gene, showing how they affect Kv channel function and lead to distinct developmental defects in ear development.

Transcriptome profile of the zebrafish atrioventricular canal reveals molecular signatures of pacemaker and valve mesenchyme

The paper profiles the transcriptome of the zebrafish atrioventricular canal to identify molecular signatures of pacemaker and valve mesenchyme, revealing conserved features with mammalian AV node and cardiac valves.

High behavioural variability mediated by altered neuronal excitability in auts2 mutant zebrafish

This study investigates the role of Auts2a in zebrafish escape behavior, finding that mutations lead to neuronal excitability issues and behavioral variability.

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

The paper investigates how Wnt3 spreads in the zebrafish brain through diffusion and molecular interactions, showing its binding to HSPG and Lrp5.

Evolutionary context can clarify teleosts gene names

The paper establishes an evolutionary-based method to correct gene naming in teleosts by comparing synteny with the spotted gar genome, identifying and validating misnamed ohnologs.