Thorsten Wohland

The paper introduces ImFCSViT, a Vision Transformer framework that improves fluorescence correlation spectroscopy by directly analyzing raw image data and extracting biophysical parameters more efficiently than traditional methods.

The paper measures morphogen diffusion in zebrafish embryos and shows that diffusion slows due to receptor binding, with implications for gradient formation.

The paper develops a two-colour ImFCS method to quantify how the juxta-membrane actin cortex influences plasma membrane dynamics by measuring reporter diffusion.

This study uses SRRFnTIRF to show EGFR does not directly interact with cortical actin, with dynamics and organization independent of actin.

The paper shows that tissue architecture and receptor binding can explain the transition from local to global morphogen diffusion, without needing additional regulatory mechanisms.

The paper uses imaging surface plasmon resonance and fluorescence correlation spectroscopy to study toxin-glycolipid interactions and their lipid dependencies on artificial and cellular membranes.

The paper shows that Midkine and Ptprz1b regulate Wnt/PCP pathway activity to coordinate midline formation in zebrafish hindbrain development.

This study investigates Bicoid gradient formation in Drosophila embryos, revealing spatially varying dynamic modes that explain the gradient's exponential shape.

This study investigates how DENV2C chaperone activity facilitates strand displacement during RNA rearrangement without altering the structural functionality of the cHP hairpin element.

This study shows that DENV2C switches the annealing pathway and reduces the intrinsic dynamics of the 5UTR, aiding in RNA replication.

The paper investigates how Wnt3 spreads in the zebrafish brain through diffusion and molecular interactions, showing its binding to HSPG and Lrp5.

The paper quantifies Sox2 and Oct4 synergistic binding to Sox/Oct motifs, showing Sox2 levels drive Fgf4 expression, influencing cell fate decisions in mouse embryos.