Author

Shrinidhi Kittur

University of Virginia Health System

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Alexis R. Boscia· 2 shared Manoj K. PateliD· 2 shared Raquel M. MirallesiD· 2 shared Atum M. Buo· 1 shared Caeley M Reever· 1 shared Charles R. FarberiD· 1 shared Eric R. WengertiD· 1 shared Erik J. FleischeliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioengineering

Alexis R. Boscia

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Base Editing Rescue of Seizures and SUDEP in SCN8A Developmental Epileptic Encephalopathy

Caeley M Reever, Alexis R. Boscia, Tyler C J Deutsch, Mansi P. Patel, Raquel M. Miralles, Shrinidhi Kittur, Erik J. Fleischel, Atum M. Buo, Matthew S. Yorek, Miriam H. Meisler, Charles R. Farber, Manoj K. Patel

This study uses base editing to correct the SCN8A R1872W mutation in mice, reducing seizures and improving survival and comorbidities.

bioRxiv · Apr 9, 2025 · PreprintBioengineering

Parvalbumin Interneuron Impairment Leads to Synaptic Transmission Deficits and Seizures in SCN8A Epileptic Encephalopathy

Raquel M. Miralles, Alexis R. Boscia, Shrinidhi Kittur, Shreya R. Vundela, Eric R. Wengert, Manoj K. Patel

This study shows that impairments in parvalbumin interneurons due to SCN8A mutations cause synaptic transmission deficits and seizures in a mouse model of SCN8A epileptic encephalopathy.

bioRxiv · Feb 9, 2024 · PreprintNeuroscience