The Cryo-EM structure of TRPC1 and TRPC5 heterotetramer
Yixiang Chen, Tong Che, Xinyu Cheng, Xiaoqiang Yang, Ying Fu, Wei Yan Zhang, Sijia Lv, Tingting Yang, Qi Peng, Weiwei Nan, Shuangyan Wan, Yaoguang Hua, Juncheng Li, Xiaoyun Wu, Hu Han, , Jin Zhang
The paper reports the cryo-EM structure of TRPC1/5 heterotetramer, revealing structural features that differentiate it from TRPC5 homomers and provide insights into its functional properties.
bioRxiv · Nov 3, 2024 · PreprintBiophysics