DICAR-JP Regulates Ribosome Migration, a New Theory of Mitochondrial Protein Production
Jun Zhang, Xueting Yu, Sihui Zheng, Gan Qiao, Chao Zhang, Siyi Tang, Xiaoping Gao, Yibin Wang, Yajun Yu, Jun Cheng, Ming Lei, Pengyun Li, Yan Yang, Chunxiang Zhang, Qiong Yuan
This paper identifies DICAR-JP as a functional domain that interacts with NAC to regulate OGDHL nascent peptide expression and mitochondrial translocation, proposing a new theory of ribosome migration in diabetic cardiomyopathy.
bioRxiv · Apr 11, 2025 · PreprintPharmacology & Toxicology