Ming Lei

This study investigates the role of lysosomal Ca2+ signaling in heart rhythm and atrial function, finding that NAADP pathway inhibition affects SAN pacemaker activity and cAMP production in atrial myocytes.

This study identifies cardiac involvement in Niemann-Pick type C through ECG abnormalities, fibrosis, and transcriptomic changes in patients and Npc1-/- mice.

This paper identifies DICAR-JP as a functional domain that interacts with NAC to regulate OGDHL nascent peptide expression and mitochondrial translocation, proposing a new theory of ribosome migration in diabetic cardiomyopathy.

This study uses molecular modeling and simulations to show that N-linked glycans on Nav channel alpha-subunits may block beta-subunit Ig-domain binding and influence channel clustering.