Author

Silvana Konermann

Primary ORCID profile (0000-0001-7915-1685 · 13 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Silvana KonermanniD13 papers · Arc Research Institute

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1

Frequent Co-Authors

Feng ZhangiD· 2 shared Jonathan S Gootenberg· 2 shared Julia JoungiD· 2 shared Omar O Abudayyeh· 2 shared Aviv RegeviD· 1 shared David BT Cox· 1 shared Ekaterina SemenovaiD· 1 shared Eric S Lander· 1 shared

Activity by Year

2016-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Feng ZhangORCID

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2 papers

Recent·Most cited

Protocol: Genome-scale CRISPR-Cas9 Knockout and Transcriptional Activation Screening

Julia Joung, Silvana Konermann, Jonathan S Gootenberg, Omar O Abudayyeh, Randall J Platt, Mark D Brigham, Neville E Sanjana, Feng Zhang

This paper describes a protocol for genome-scale CRISPR-Cas9 knockout and transcriptional activation screening, including library design, validation strategies, and timing estimates.

Nature Protocols · Mar 23, 2017Peer-reviewedMolecular Biology

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

Omar O Abudayyeh, Jonathan S Gootenberg, Silvana Konermann, Julia Joung, Ian M Slaymaker, David BT Cox, Sergey Shmakov, Kira S Makarova, Ekaterina Semenova, Leonid Minakhin, Konstantin Severinov, Aviv Regev, Eric S Lander, Eugene V Koonin, Feng Zhang

This study characterizes C2c2, a CRISPR-Cas effector that uses an RNA guide to target and cleave RNA, showing its potential as a programmable RNA-targeting tool.

Science · Aug 5, 2016Peer-reviewedMolecular Biology