Author

Silvia Cachaco

George Mason University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Hongyan SuiiD· 1 shared Jun YangiD· 1 shared Qian Chen· 1 shared Rosana A. Wiscovitch-RussoiD· 1 shared Sylvain LaverdureiD· 1 shared Tomozumi ImamichiiD· 1 shared Whitney Bruchey· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Hongyan SuiORCID

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1 paper

Recent·Most cited

Manganese mediates antiviral effects by driving an ATM -TBK1 phosphorylation signaling pathway

Hongyan Sui, Rosana A. Wiscovitch-Russo, Silvia Cachaco, Jun Yang, Whitney Bruchey, Sylvain Laverdure, Qian Chen, Tomozumi Imamichi

This paper identifies a manganese-induced ATM-TBK1 phosphorylation pathway that enhances antiviral immunity by promoting cytokine production and suppressing HIV replication.

Frontiers in Immunology · Nov 19, 2025Peer-reviewedImmunology