Tomozumi Imamichi

This study shows IL-27 reduces cell-surface LDLR in macrophages and limits VSV-G-pseudotyped HIV infection through receptor downregulation and post-entry mechanisms.

The paper shows miRTC14 activates IFN expression through interaction with pyruvate carboxylase and LGP2, leading to TBK1 phosphorylation and IFN subtype production.

This study shows that mTOR hyperactivity in STRADA-deficient brain organoids causes delayed neurogenesis and altered interneuron fate, which can be rescued by rapamycin.

This paper identifies a manganese-induced ATM-TBK1 phosphorylation pathway that enhances antiviral immunity by promoting cytokine production and suppressing HIV replication.

The paper compares plasmid yield from different bacterial growth tubes and finds that Oxford conical-polypropylene tubes produce 1.5-fold more plasmid DNA than other polypropylene tubes.