Author

Silvia Detro‐Dassen

Universitätsklinikum Aachen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:deep learning· 1 Assay:electrophysiology· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Angelika LampertiD· 2 shared Petra A. I. Hautvast· 2 shared Ralf HausmanniD· 2 shared Amdiya Botchoi· 1 shared Anika NeureiteriD· 1 shared Annika H. Rühlmann· 1 shared Carène BenasoloiD· 1 shared Christian NeuhofiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Angelika LampertORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 21, 2026

Outer Pore Collapse as a Potential Mechanism of Partial Loss of Pain in Nav1.7 M899I

Vishal Sudha Bhagavath Eswaran, Estefania Torres-Ortiz, Petra A. I. Hautvast…·Angelika Lampert

The paper investigates the M899I variant in Nav1.7, showing it causes pore collapse, leading to loss of sodium currents and pain insensitivity.

DOI 10.64898/2026.08.18.745213

humanelectrophysiology

𝕏 PostBluesky

NeuroscienceBritish Journal of PharmacologyPeer-reviewedJul 14, 2020

Uncoupling sodium channel dimers rescues phenotype of pain-linked Nav1.7 mutation

Annika H. Rühlmann, Jannis Körner, Ralf Hausmann…·Angelika Lampert

The paper shows that uncoupling dimerized Nav1.7 channels reduces persistent current caused by a pain mutation, suggesting dimerization plays a role in pain syndromes.

29 citations

humanexperimental assay

𝕏 PostBluesky