Author

Vishal Sudha Bhagavath Eswaran

Universitätsklinikum AachenORCID 0000-0001-7393-3811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Angelika LampertiD· 2 shared Alessia PiergentiliiD· 1 shared Amdiya Botchoi· 1 shared Anika NeureiteriD· 1 shared Estefania Torres-OrtiziD· 1 shared Giulia RossettiiD· 1 shared Paulo C. T. SouzaiD· 1 shared Petra A. I. Hautvast· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Angelika LampertORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 21, 2026

Outer Pore Collapse as a Potential Mechanism of Partial Loss of Pain in Nav1.7 M899I

Vishal Sudha Bhagavath Eswaran, Estefania Torres-Ortiz, Petra A. I. Hautvast…·Angelika Lampert

The paper investigates the M899I variant in Nav1.7, showing it causes pore collapse, leading to loss of sodium currents and pain insensitivity.

DOI 10.64898/2026.08.18.745213

humanelectrophysiology

𝕏 PostBluesky

PhysiologyInternational Journal of Biological MacromoleculesPeer-reviewedAug 7, 2024

Depletion of membrane cholesterol modifies structure, dynamic and activation of Nav1.7

Simone Albani, Vishal Sudha Bhagavath Eswaran, Alessia Piergentili…·Giulia Rossetti

This study shows that cholesterol depletion alters Nav1.7 structure and function, affecting its gating and drug response, with implications for pain management.

10 citations

humanelectrophysiology

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