Author

Simon Lesbirel

Jackson Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Ashley TuckeriD· 1 shared Benjamin E. LowiD· 1 shared Carol J. BultiD· 1 shared Heidi J. Munger· 1 shared Jeremy R. Charette· 1 shared Julie M. WellsiD· 1 shared Michael V. WilesiD· 1 shared Naomi Mitchell-HutchinsoniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Ashley TuckerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell-type Specific Alteration of Dicer1 Accelerates Tumor Progression in Mouse Models of KRAS-driven Lung Adenocarcinoma

Julie M. Wells, Richard S. Maser, Rosalinda A. Doty, Ashley Tucker, Wendy Memishian, Teresa McGee, Naomi Mitchell-Hutchinson, Paige Ramkissoon, Simon Lesbirel, Jeremy R. Charette, Heidi J. Munger, Travis Beckett, Carol J. Bult

This study shows that cell-type-specific Dicer1 disruption accelerates KRAS-driven lung adenocarcinoma progression in mice, highlighting non-cell-autonomous miRNA-mediated effects.

bioRxiv · Jun 1, 2026 · PreprintCancer Biology

Efficient targeted transgenesis of large donor DNA into multiple mouse genetic backgrounds using bacteriophage Bxb1 integrase

Benjamin E. Low, Vishnu Hosur, Simon Lesbirel, Michael V. Wiles

This paper develops a method for efficient targeted transgenesis of large DNA constructs into multiple mouse genetic backgrounds using Bxb1 integrase, achieving high integration efficiency and precise insertion.

Scientific Reports · Mar 31, 2022Peer-reviewedGenetics