Author

Simona Cugusi

The Francis Crick Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anouk M. OlthofiD· 1 shared Jesper Qualmann SvejstrupiD· 1 shared Melvin Noé GonzáleziD· 1 shared Nanna Bach Poulsen· 1 shared Nicolás Nieto MorenoiD· 1 shared Theodora Bautu· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperSystems Biology

Anouk M. OlthofORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Systems-level feedback loops maintain gene expression homeostasis following RNA polymerase II dosage perturbation

Anouk M. Olthof, Melvin Noé González, Nanna Bach Poulsen, Nicolás Nieto Moreno, Theodora Bautu, Simona Cugusi, Jesper Qualmann Svejstrup

The paper shows that reducing RNA polymerase II levels disrupts transcriptional homeostasis through organized gene expression changes and feedback loops.

bioRxiv · Sep 18, 2025 · PreprintSystems Biology