Jesper Qualmann Svejstrup

The paper identifies a direct interaction between Integrator and NELF that regulates transcriptional pausing and premature termination.

The paper identifies ZAKα as a sensor that detects mRNA stasis at the ribosomal exit channel through interactions with ribosomal proteins and rRNA.

The paper shows that reducing RNA polymerase II levels disrupts transcriptional homeostasis through organized gene expression changes and feedback loops.

The paper shows PAF1C allosterically activates CDK12/13 kinase to phosphorylate RNA polymerase II CTD during transcript elongation.

This study identifies STK19 as a factor facilitating the transition from initial TCR complex assembly to downstream repair steps by enabling RNAPII clearance.

This study investigates the role of ELP1 in neuronal development by analyzing transcriptomes of mouse embryos with varying ELP1 levels, finding that ELP1 regulates gene expression and neuronal development.